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Programme of the 12th Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment

08:00 Registration
Opening remarks
09:00 Opening and welcome Peter Reiss (SHM; Amsterdam UMC, UvA; AIGHD, Amsterdam)
Session 1: Advances and Barriers in Optimising HIV Care
Chairs:  Jan Prins (Amsterdam UMC, AMC site, Amsterdam) & Jet Gisolf (Rijnstate, Arnhem)
09:10-09:40 Plenary:  ART: a changing landscape Prof. Chloe Orkin (Barts Health NHS Trust, London, UK)
09:40-09:50 Large cost-savings of splitting a single-tablet regimen (STR) to a two-tablet regimen (TTR), containing the same antiretrovirals Piter Oosterhof (OLVG, Amsterdam; Radboudumc, Nijmegen)
09:50-10:00 Substantial transmission of the M28V resistant associated variant among acute hepatitis C HIV co-infected men-who-have-sex-with-men Stephanie Popping (Erasmus MC, Rotterdam)
10:00-10:10 HIV as a chronic condition: Experienced burden of living with HIV today among men who have sex with men in the Netherlands Ward van Bilsen (GGD Amsterdam, Amsterdam)
10:00-10:20 Reasons for late presentation among older MSM in Amsterdam Maarten Bedert (AIGHD; GGD Amsterdam, Amsterdam)
10:20-11:05 Moderated panel discussion: Highlights from the 2019 HIV Monitoring Report Moderator: Alexander Pastoors (Hiv Vereniging)
Speakers: Ard van Sighem, Anders Boyd, Colette Smit en Ferdinand Wit (SHM, Amsterdam)
Panel: Jan Prins (Amsterdam UMC, AMC site), Jet Gisolf (Rijnstate, Arnhem), Gerjanne ter Beest (Rijnstate, Arnhem)
11:05-11:35 Refreshment break & poster viewing
Session 2: From Conception to Infancy and Beyond
Chairs:  David Burger (Radboudumc, Nijmegen) & Liesbeth van Leeuwen (Amsterdam UMC, UvA, Amsterdam)
11:35-12:05 Plenary:  Challenges and needs for women living with HIV: From conception to infancy Dr. Karoline Aebi-Popp (University Hospital Bern, Switzerland)
12:05-12:15 White matter hyperintensity expansion in long-term treated perinatally HIV-infected adolescents: a longitudinal neuroimaging study. Malon van den Hof (Amsterdam UMC, UvA, Amsterdam)
12:15-12:25 Cerebral organoids as a novel 3D cell culture model to investigate the neuropathogenesis of HIV Stephanie Gumbs (UMC Utrecht, Utrecht)
12:25-13:45 Lunch and poster viewing + guided walk tours
Session 3: Science to Advance the Response
Chairs:  Peter Reiss (SHM; Amsterdam UMC, AMC site; AIGHD, Amsterdam) & Monique Nijhuis (UMC Utrecht, Utrecht)
13:45-14:15 Keynote:  Ending the HIV Pandemic: Challenges and Opportunities Dr. Anthony Fauci (NIH/NIAID, Bethesda, USA)
14:15-14:25 Genetic variations in the host dependency factors ALCAM and TPST2 impact HIV-1 disease progression Zita Kruize (Amsterdam UMC, UvA, Amsterdam)
14:25-14:35 Harm reduction revisited: The causal effect of the Dutch approach towards people who inject drugs on HIV infection risk in Amsterdam, the Netherlands Anders Boyd (GGD Amsterdam, Amsterdam)
14:35-14:45 Sexual behaviour and perceived risk of HIV between 1999 and 2018 among men who have sex with men in Amsterdam, the Netherlands Ganna Rozhnova (UMC Utrecht, Utrecht)
14:45-14:55 Inducing cell death: an approach to selectively target viral RNA expressing cells to eliminate the HIV-1 reservoir Shringar Rao (Erasmus MC, Rotterdam)
14:55-15:05 Repurposing of clinically-approved autophagy drugs for combinatory prophylactic and therapeutic HIV-1 therapies Alexandra Cloherty (Amsterdam UMC, UvA, Amsterdam)
15:05-15:40  Refreshment break 
Session 4: From the Bench to the Community
Chairs:  Kim Sigaloff (Amsterdam UMC, VUmc site) & Eric van Gorp (Erasmus MC, Rotterdam)
15:40-16:10 PlenaryBringing precision to the global HIV response Prof. Wafaa El-Sadr (Columbia University, New York, USA)
16:10-16:20 Antibodies from rabbits immunized with clade B SOSIP trimers can neutralize despite unusual approach angles Marlies van Haaren (Amsterdam UMC, UvA, Amsterdam)
16:20-16:30 Comparison of monoclonal antibodies induced by HIV-1 envelop glycoprotein immunization and SHIV infection in non-human primates to guide HIV vaccine design Jelle van Schooten (Amsterdam UMC, UvA, Amsterdam)
16:30-16:40 Frequency and determinants of switching between daily and event-driven PrEP and discontinuing each regimen among men who have sex with men participating in the Amsterdam PrEP demonstration project Liza Coyer (GGD Amsterdam, Amsterdam)
16:40-16:50 Offering a choice of daily and event-driven PrEP for MSM: a cost-effectiveness analysis Albert Jan van Hoek (RIVM, Bilthoven)
16:50-17:00 Using a daily mobile application and dried blot spots to measure adherence to event-driven PrEP among participants of the AMPrEP cohort study Vita Jongen (GGD Amsterdam, Amsterdam)
17:00-17:15 Closing & presentation of Joep Lange and Jacqueline van Tongeren young investigator award Peter Reiss (SHM; Amsterdam UMC, UvA; AIGHD, Amsterdam)
17:30 Drinks